Cargando…
The influence of the rs6295 gene polymorphism on serotonin-1A receptor distribution investigated with PET in patients with major depression applying machine learning
Major depressive disorder (MDD) is the most common neuropsychiatric disease and despite extensive research, its genetic substrate is still not sufficiently understood. The common polymorphism rs6295 of the serotonin-1A receptor gene (HTR1A) is affecting the transcriptional regulation of the 5-HT(1A)...
Autores principales: | Kautzky, A, James, G M, Philippe, C, Baldinger-Melich, P, Kraus, C, Kranz, G S, Vanicek, T, Gryglewski, G, Wadsak, W, Mitterhauser, M, Rujescu, D, Kasper, S, Lanzenberger, R |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537636/ https://www.ncbi.nlm.nih.gov/pubmed/28608854 http://dx.doi.org/10.1038/tp.2017.108 |
Ejemplares similares
-
Epistasis of HTR1A and BDNF risk genes alters cortical 5-HT1A receptor binding: PET results link genotype to molecular phenotype in depression
por: Kautzky, Alexander, et al.
Publicado: (2019) -
Correction: Epistasis of HTR1A and BDNF risk genes alters cortical 5-HT1A receptor binding: PET results link genotype to molecular phenotype in depression
por: Kautzky, Alexander, et al.
Publicado: (2019) -
Effects of Selective Serotonin Reuptake Inhibitors on Interregional Relation of Serotonin Transporter Availability in Major Depression
por: James, Gregory M., et al.
Publicado: (2017) -
PS168. Hybrid PET/MR imaging of serotonin transporter occupancy and brain activation to elucidate the mechanism of action of selective serotonin reuptake inhibitors
por: Gryglewski, G, et al.
Publicado: (2016) -
Exploring the Impact of BDNF Val66Met Genotype on Serotonin Transporter and Serotonin-1A Receptor Binding
por: Kraus, Christoph, et al.
Publicado: (2014)