Cargando…

Mice lacking the chromodomain helicase DNA-binding 5 chromatin remodeler display autism-like characteristics

Although autism spectrum disorders (ASDs) share a core set of nosological features, they exhibit substantial genetic heterogeneity. A parsimonious hypothesis posits that dysregulated epigenetic mechanisms represent common pathways in the etiology of ASDs. To investigate this hypothesis, we generated...

Descripción completa

Detalles Bibliográficos
Autores principales: Pisansky, M T, Young, A E, O'Connor, M B, Gottesman, I I, Bagchi, A, Gewirtz, J C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537637/
https://www.ncbi.nlm.nih.gov/pubmed/28608855
http://dx.doi.org/10.1038/tp.2017.111