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Mice lacking the chromodomain helicase DNA-binding 5 chromatin remodeler display autism-like characteristics
Although autism spectrum disorders (ASDs) share a core set of nosological features, they exhibit substantial genetic heterogeneity. A parsimonious hypothesis posits that dysregulated epigenetic mechanisms represent common pathways in the etiology of ASDs. To investigate this hypothesis, we generated...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537637/ https://www.ncbi.nlm.nih.gov/pubmed/28608855 http://dx.doi.org/10.1038/tp.2017.111 |