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2BC Non-Structural Protein of Enterovirus A71 Interacts with SNARE Proteins to Trigger Autolysosome Formation

Viruses have evolved unique strategies to evade or subvert autophagy machinery. Enterovirus A71 (EV-A71) induces autophagy during infection in vitro and in vivo. In this study, we report that EV-A71 triggers autolysosome formation during infection in human rhabdomyosarcoma (RD) cells to facilitate i...

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Detalles Bibliográficos
Autores principales: Lai, Jeffrey K. F., Sam, I-Ching, Verlhac, Pauline, Baguet, Joël, Eskelinen, Eeva-Liisa, Faure, Mathias, Chan, Yoke Fun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537661/
https://www.ncbi.nlm.nih.gov/pubmed/28677644
http://dx.doi.org/10.3390/v9070169