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Telomeres and Telomerase: Role in Marek’s Disease Virus Pathogenesis, Integration and Tumorigenesis

Telomeres protect the ends of vertebrate chromosomes from deterioration and consist of tandem nucleotide repeats (TTAGGG)(n) that are associated with a number of proteins. Shortening of the telomeres occurs during genome replication, thereby limiting the replication potential of somatic cells. To co...

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Detalles Bibliográficos
Autores principales: Kheimar, Ahmed, Previdelli, Renato L., Wight, Darren J., Kaufer, Benedikt B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537665/
https://www.ncbi.nlm.nih.gov/pubmed/28677643
http://dx.doi.org/10.3390/v9070173