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Targeted O‐glycoproteomics explored increased sialylation and identified MUC16 as a poor prognosis biomarker in advanced‐stage bladder tumours

Bladder carcinogenesis and tumour progression is accompanied by profound alterations in protein glycosylation on the cell surface, which may be explored for improving disease management. In a search for prognosis biomarkers and novel therapeutic targets we have screened, using immunohistochemistry,...

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Detalles Bibliográficos
Autores principales: Cotton, Sofia, Azevedo, Rita, Gaiteiro, Cristiana, Ferreira, Dylan, Lima, Luís, Peixoto, Andreia, Fernandes, Elisabete, Neves, Manuel, Neves, Diogo, Amaro, Teresina, Cruz, Ricardo, Tavares, Ana, Rangel, Maria, Silva, André M. N., Santos, Lúcio Lara, Ferreira, José Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537688/
https://www.ncbi.nlm.nih.gov/pubmed/28156048
http://dx.doi.org/10.1002/1878-0261.12035