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Impact of somatic copy number alterations on the glioblastoma miRNome: miR‐4484 is a genomically deleted tumour suppressor

Glioblastoma (GBM) is the most frequent and most malignant primary brain tumour in adults. GBMs have a unique landscape of somatic copy number alterations (SCNAs), with the concomitant appearance of numerous driver amplifications and deletions. Here, we examined the genomic regions harbouring SCNAs...

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Detalles Bibliográficos
Autores principales: Nawaz, Zahid, Patil, Vikas, Thinagararjan, Sivaarumugam, Rao, Soumya A., Hegde, Alangar S., Arivazhagan, Arimappamagan, Santosh, Vani, Somasundaram, Kumaravel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537698/
https://www.ncbi.nlm.nih.gov/pubmed/28378523
http://dx.doi.org/10.1002/1878-0261.12060