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Stromal SPOCK1 supports invasive pancreatic cancer growth

Pancreatic ductal adenocarcinoma (PDAC) is marked by an abundant stromal deposition. This stroma is suspected to harbor both tumor‐promoting and tumor‐suppressing properties. This is underscored by the disappointing results of stroma targeting in clinical studies. Given the complexity of tumor–strom...

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Detalles Bibliográficos
Autores principales: Veenstra, Veronique L., Damhofer, Helene, Waasdorp, Cynthia, Steins, Anne, Kocher, Hemant M., Medema, Jan P., van Laarhoven, Hanneke W., Bijlsma, Maarten F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537700/
https://www.ncbi.nlm.nih.gov/pubmed/28486750
http://dx.doi.org/10.1002/1878-0261.12073