Synergistic activity of everolimus and 5‐aza‐2′‐deoxycytidine in medullary thyroid carcinoma cell lines

Medullary thyroid cancer (MTC) is a tumor highly resistant to chemo‐ and radiotherapy. Drug resistance can be induced by epigenetic changes such as aberrant DNA methylation. To overcome drug resistance, we explored a promising approach based on the use of 5‐aza‐2′‐deoxycytidine (AZA), a demethylatin...

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Detalles Bibliográficos
Autores principales: Vitale, Giovanni, Dicitore, Alessandra, Pepe, Daniele, Gentilini, Davide, Grassi, Elisa S., Borghi, Maria O., Gelmini, Giulia, Cantone, Maria C., Gaudenzi, Germano, Misso, Gabriella, Di Blasio, Anna M., Hofland, Leo J., Caraglia, Michele, Persani, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537710/
https://www.ncbi.nlm.nih.gov/pubmed/28453190
http://dx.doi.org/10.1002/1878-0261.12070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537710/
https://www.ncbi.nlm.nih.gov/pubmed/28453190
http://dx.doi.org/10.1002/1878-0261.12070

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