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Asymmetric Structure of the Dimerization Domain of PhoR, a Sensor Kinase Important for the Virulence of Mycobacterium tuberculosis

[Image: see text] The PhoP–PhoR two-component system is essential for the virulence of Mycobacterium tuberculosis (Mtb) and therefore represents a potential target for developing novel antituberculosis therapies. However, little is known about the mechanism by which this two-component system regulat...

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Detalles Bibliográficos
Autores principales: Xing, Daniel, Ryndak, Michelle B., Wang, Liqin, Kolesnikova, Irina, Smith, Issar, Wang, Shuishu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537716/
https://www.ncbi.nlm.nih.gov/pubmed/28782049
http://dx.doi.org/10.1021/acsomega.7b00612