LXRα Regulates Hepatic ChREBPα Activity and Lipogenesis upon Glucose, but Not Fructose Feeding in Mice

Liver X receptors (LXRα/β) and carbohydrate response element-binding proteins (ChREBPα/β) are key players in the transcriptional control of hepatic de novo lipogenesis. LXRα/β double knockout (LXRα(−/−)/β(−/−)) mice have reduced feeding-induced nuclear O-linked N-acetylglucosamine (O-GlcNAc) signali...

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Detalles Bibliográficos
Autores principales: Fan, Qiong, Nørgaard, Rikke C., Bindesbøll, Christian, Lucas, Christin, Dalen, Knut Tomas, Babaie, Eshrat, Itkonen, Harri M., Matthews, Jason, Nebb, Hilde I., Grønning-Wang, Line M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537793/
https://www.ncbi.nlm.nih.gov/pubmed/28661453
http://dx.doi.org/10.3390/nu9070678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537793/
https://www.ncbi.nlm.nih.gov/pubmed/28661453
http://dx.doi.org/10.3390/nu9070678

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