Immunoassays for the quantification of ALK and phosphorylated ALK support the evaluation of on‐target ALK inhibitors in neuroblastoma

Targeted inhibition of anaplastic lymphoma kinase (ALK) is a successful approach for the treatment of many ALK‐aberrant malignancies; however, the presence of resistant mutations necessitates both the development of more potent compounds and pharmacodynamic methods with which to determine their effi...

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Detalles Bibliográficos
Autores principales: Tucker, Elizabeth R., Tall, Jennifer R., Danielson, Laura S., Gowan, Sharon, Jamin, Yann, Robinson, Simon P., Banerji, Udai, Chesler, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537911/
https://www.ncbi.nlm.nih.gov/pubmed/28432815
http://dx.doi.org/10.1002/1878-0261.12069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537911/
https://www.ncbi.nlm.nih.gov/pubmed/28432815
http://dx.doi.org/10.1002/1878-0261.12069

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