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Immunoassays for the quantification of ALK and phosphorylated ALK support the evaluation of on‐target ALK inhibitors in neuroblastoma
Targeted inhibition of anaplastic lymphoma kinase (ALK) is a successful approach for the treatment of many ALK‐aberrant malignancies; however, the presence of resistant mutations necessitates both the development of more potent compounds and pharmacodynamic methods with which to determine their effi...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537911/ https://www.ncbi.nlm.nih.gov/pubmed/28432815 http://dx.doi.org/10.1002/1878-0261.12069 |