Generation, repair and replication of guanine oxidation products

Guanine is the most readily oxidized of the four DNA bases, and guanine oxidation products cause G:C-T:A and G:C-C:G transversions through DNA replication. 8-Oxo-7,8-dihydroguanine (8-oxoG) causes G:C-T:A transversions but not G:C-C:G transversions, and is more readily oxidized than guanine. This re...

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Detalles Bibliográficos
Autores principales: Kino, Katsuhito, Hirao-Suzuki, Masayo, Morikawa, Masayuki, Sakaga, Akane, Miyazawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537945/
https://www.ncbi.nlm.nih.gov/pubmed/28781714
http://dx.doi.org/10.1186/s41021-017-0081-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537945/
https://www.ncbi.nlm.nih.gov/pubmed/28781714
http://dx.doi.org/10.1186/s41021-017-0081-0

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