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Enriched endoplasmic reticulum-mitochondria interactions result in mitochondrial dysfunction and apoptosis in oocytes from obese mice

BACKGROUND: Maternal obesity alters oocytes and subsequent fetal metabolism. An increasing number of studies have shown that the endoplasmic reticulums (ER) or mitochondria have important effects on oocyte quality, but there has been no study of the effect of mitochondria-associated ER membranes (MA...

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Detalles Bibliográficos
Autores principales: Zhao, Lihong, Lu, Tengfei, Gao, Lei, Fu, Xiangwei, Zhu, Shien, Hou, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537973/
https://www.ncbi.nlm.nih.gov/pubmed/28781772
http://dx.doi.org/10.1186/s40104-017-0195-z