Impact of CYP2C19 Genotype and Liver Function on Voriconazole Pharmacokinetics in Renal Transplant Recipients

BACKGROUND: Invasive fungal infection (IFI) is one of the leading causes of early death after renal transplantation. Voriconazole (VRC) is the first-line drug of IFI. Because of the large inter- and intraindividual variability in VRC plasma concentrations and the narrow therapeutic window for treati...

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Detalles Bibliográficos
Autores principales: Li, Zi-Wei, Peng, Feng-Hua, Yan, Miao, Liang, Wu, Liu, Xiao-Lei, Wu, Yan-Qin, Lin, Xiao-Bin, Tan, Sheng-Lan, Wang, Feng, Xu, Ping, Fang, Ping-Fei, Liu, Yi-Ping, Xiang, Da-Xiong, Zhang, Bi-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Therapeutic Drug Monitoring 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538305/
https://www.ncbi.nlm.nih.gov/pubmed/28604474
http://dx.doi.org/10.1097/FTD.0000000000000425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538305/
https://www.ncbi.nlm.nih.gov/pubmed/28604474
http://dx.doi.org/10.1097/FTD.0000000000000425

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