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Comprehensive definition of human immunodominant CD8 antigens in tuberculosis

Despite widespread use of the Bacillus Calmette-Guerin vaccine, tuberculosis, caused by infection with Mycobacterium tuberculosis, remains a leading cause of morbidity and mortality worldwide. As CD8(+) T cells are critical to tuberculosis host defense and a phase 2b vaccine trial of modified vaccin...

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Detalles Bibliográficos
Autores principales: Lewinsohn, Deborah A., Swarbrick, Gwendolyn M., Park, Byung, Cansler, Meghan E., Null, Megan D., Toren, Katelynne G., Baseke, Joy, Zalwango, Sarah, Mayanja-Kizza, Harriet, Malone, LaShaunda L., Nyendak, Melissa, Wu, Guanming, Guinn, Kristi, McWeeney, Shannon, Mori, Tomi, Chervenak, Keith A., Sherman, David R., Boom, W. Henry, Lewinsohn, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538316/
https://www.ncbi.nlm.nih.gov/pubmed/28775896
http://dx.doi.org/10.1038/s41541-017-0008-6