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Jak Inhibitors Modulate Production of Replication-Competent Zika Virus in Human Hofbauer, Trophoblasts, and Neuroblastoma cells

Zika Virus (ZIKV) is a flavivirus that has been implicated in causing brain deformations, birth defects, and microcephaly in fetuses, and associated with Guillain-Barre syndrome. Mechanisms responsible for transmission of ZIKV across the placenta to the fetus are incompletely understood. Herein, we...

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Detalles Bibliográficos
Autores principales: Gavegnano, Christina, Bassit, Leda C., Cox, Bryan D., Hsiao, Hui-Mien, Johnson, Erica L., Suthar, Mehul, Chakraborty, Rana, Schinazi, Raymond F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pathogens and Immunity 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538373/
https://www.ncbi.nlm.nih.gov/pubmed/28776046
http://dx.doi.org/10.20411/pai.v2i2.190