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Prdm16 is required for the maintenance of neural stem cells in the postnatal forebrain and their differentiation into ependymal cells

We and others showed previously that PR domain-containing 16 (Prdm16) is a transcriptional regulator required for stem cell function in multiple fetal and neonatal tissues, including the nervous system. However, Prdm16 germline knockout mice died neonatally, preventing us from testing whether Prdm16...

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Detalles Bibliográficos
Autores principales: Shimada, Issei S., Acar, Melih, Burgess, Rebecca J., Zhao, Zhiyu, Morrison, Sean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538436/
https://www.ncbi.nlm.nih.gov/pubmed/28698301
http://dx.doi.org/10.1101/gad.291773.116