GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression

The eIF4E homologous protein (4EHP) is thought to repress translation by competing with eIF4E for binding to the 5′ cap structure of specific mRNAs to which it is recruited through interactions with various proteins, including the GRB10-interacting GYF (glycine–tyrosine–phenylalanine domain) protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Peter, Daniel, Weber, Ramona, Sandmeir, Felix, Wohlbold, Lara, Helms, Sigrun, Bawankar, Praveen, Valkov, Eugene, Igreja, Cátia, Izaurralde, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538437/
https://www.ncbi.nlm.nih.gov/pubmed/28698298
http://dx.doi.org/10.1101/gad.299420.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538437/
https://www.ncbi.nlm.nih.gov/pubmed/28698298
http://dx.doi.org/10.1101/gad.299420.117

Ejemplares similares