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Human skin dendritic cell fate is differentially regulated by the monocyte identity factor Kruppel-like factor 4 during steady state and inflammation

BACKGROUND: Langerhans cell (LC) networks play key roles in immunity and tolerance at body surfaces. LCs are established prenatally and can be replenished from blood monocytes. Unlike skin-resident dermal DCs (dDCs)/interstitial-type DCs and inflammatory dendritic epidermal cells appearing in dermat...

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Detalles Bibliográficos
Autores principales: Jurkin, Jennifer, Krump, Corinna, Köffel, René, Fieber, Christina, Schuster, Christopher, Brunner, Patrick M., Borek, Izabela, Eisenwort, Gregor, Lim, Clarice, Mages, Jörg, Lang, Roland, Bauer, Wolfgang, Mechtcheriakova, Diana, Meshcheryakova, Anastasia, Elbe-Bürger, Adelheid, Stingl, Georg, Strobl, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538449/
https://www.ncbi.nlm.nih.gov/pubmed/27742396
http://dx.doi.org/10.1016/j.jaci.2016.09.018