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The mammalian skeletal muscle DHPR has larger Ca(2+) conductance and is phylogenetically ancient to the early ray-finned fish sterlet (Acipenser ruthenus)

The L-type Ca(2+) channel or dihydropyridine receptor (DHPR) in vertebrate skeletal muscle is responsible for sensing sarcolemmal depolarizations and transducing this signal to the sarcoplasmic Ca(2+) release channel RyR1 via conformational coupling to initiate muscle contraction. During this excita...

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Detalles Bibliográficos
Autores principales: Schrötter, Kai, Dayal, Anamika, Grabner, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538450/
https://www.ncbi.nlm.nih.gov/pubmed/27793347
http://dx.doi.org/10.1016/j.ceca.2016.10.002