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The mammalian skeletal muscle DHPR has larger Ca(2+) conductance and is phylogenetically ancient to the early ray-finned fish sterlet (Acipenser ruthenus)
The L-type Ca(2+) channel or dihydropyridine receptor (DHPR) in vertebrate skeletal muscle is responsible for sensing sarcolemmal depolarizations and transducing this signal to the sarcoplasmic Ca(2+) release channel RyR1 via conformational coupling to initiate muscle contraction. During this excita...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538450/ https://www.ncbi.nlm.nih.gov/pubmed/27793347 http://dx.doi.org/10.1016/j.ceca.2016.10.002 |