Ancient antagonism between CELF and RBFOX families tunes mRNA splicing outcomes

Over 95% of human multi-exon genes undergo alternative splicing, a process important in normal development and often dysregulated in disease. We sought to analyze the global splicing regulatory network of CELF2 in human T cells, a well-studied splicing regulator critical to T cell development and fu...

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Detalles Bibliográficos
Autores principales: Gazzara, Matthew R., Mallory, Michael J., Roytenberg, Renat, Lindberg, John P., Jha, Anupama, Lynch, Kristen W., Barash, Yoseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538552/
https://www.ncbi.nlm.nih.gov/pubmed/28512194
http://dx.doi.org/10.1101/gr.220517.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538552/
https://www.ncbi.nlm.nih.gov/pubmed/28512194
http://dx.doi.org/10.1101/gr.220517.117

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