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The identification and functional annotation of RNA structures conserved in vertebrates

Structured elements of RNA molecules are essential in, e.g., RNA stabilization, localization, and protein interaction, and their conservation across species suggests a common functional role. We computationally screened vertebrate genomes for conserved RNA structures (CRSs), leveraging structure-bas...

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Detalles Bibliográficos
Autores principales: Seemann, Stefan E., Mirza, Aashiq H., Hansen, Claus, Bang-Berthelsen, Claus H., Garde, Christian, Christensen-Dalsgaard, Mikkel, Torarinsson, Elfar, Yao, Zizhen, Workman, Christopher T., Pociot, Flemming, Nielsen, Henrik, Tommerup, Niels, Ruzzo, Walter L., Gorodkin, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538553/
https://www.ncbi.nlm.nih.gov/pubmed/28487280
http://dx.doi.org/10.1101/gr.208652.116