Cargando…

The identification and functional annotation of RNA structures conserved in vertebrates

Structured elements of RNA molecules are essential in, e.g., RNA stabilization, localization, and protein interaction, and their conservation across species suggests a common functional role. We computationally screened vertebrate genomes for conserved RNA structures (CRSs), leveraging structure-bas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seemann, Stefan E., Mirza, Aashiq H., Hansen, Claus, Bang-Berthelsen, Claus H., Garde, Christian, Christensen-Dalsgaard, Mikkel, Torarinsson, Elfar, Yao, Zizhen, Workman, Christopher T., Pociot, Flemming, Nielsen, Henrik, Tommerup, Niels, Ruzzo, Walter L., Gorodkin, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538553/ https://www.ncbi.nlm.nih.gov/pubmed/28487280 http://dx.doi.org/10.1101/gr.208652.116

Ejemplares similares

Does rapid sequence divergence preclude RNA structure conservation in vertebrates?
por: Seemann, Stefan E, et al.
Publicado: (2022)

Transcriptomic landscape of lncRNAs in inflammatory bowel disease
por: Mirza, Aashiq H, et al.
Publicado: (2015)

Fast Pairwise Structural RNA Alignments by Pruning of the Dynamical Programming Matrix
por: Havgaard, Jakob H, et al.
Publicado: (2007)

Circulating MicroRNAs in Plasma of Hepatitis B e Antigen Positive Children Reveal Liver-Specific Target Genes
por: Winther, Thilde Nordmann, et al.
Publicado: (2014)

Cross-species high-resolution transcriptome profiling suggests biomarkers and therapeutic targets for ulcerative colitis
por: Yarani, Reza, et al.
Publicado: (2023)

Cell Type-Selective Expression of Circular RNAs in Human Pancreatic Islets
por: Kaur, Simranjeet, et al.
Publicado: (2018)

Long non-coding RNAs as novel players in β cell function and type 1 diabetes
por: Mirza, Aashiq H., et al.
Publicado: (2017)

The emerging role of lncRNAs in inflammatory bowel disease
por: Yarani, Reza, et al.
Publicado: (2018)

Independent component and pathway-based analysis of miRNA-regulated gene expression in a model of type 1 diabetes
por: Bang-Berthelsen, Claus H, et al.
Publicado: (2011)

A splice-site variant in the lncRNA gene RP1-140A9.1 cosegregates in the large Volkmann cataract family
por: Eiberg, Hans, et al.
Publicado: (2019)

Effects of GWAS-Associated Genetic Variants on lncRNAs within IBD and T1D Candidate Loci
por: Mirza, Aashiq H., et al.
Publicado: (2014)

Differential Plasma MicroRNA Profiles in HBeAg Positive and HBeAg Negative Children with Chronic Hepatitis B
por: Winther, Thilde Nordmann, et al.
Publicado: (2013)

Hepatitis B Surface Antigen Quantity Positively Correlates with Plasma Levels of microRNAs Differentially Expressed in Immunological Phases of Chronic Hepatitis B in Children
por: Winther, Thilde Nordmann, et al.
Publicado: (2013)

WAR: Webserver for aligning structural RNAs
por: Torarinsson, Elfar, et al.
Publicado: (2008)

A Dual Systems Genetics Approach Identifies Common Genes, Networks, and Pathways for Type 1 and 2 Diabetes in Human Islets
por: Kaur, Simranjeet, et al.
Publicado: (2021)

Sequence and expression analysis of gaps in human chromosome 20
por: Minocherhomji, Sheroy, et al.
Publicado: (2012)

Optimizing RNA structures by sequence extensions using RNAcop
por: Hecker, Nikolai, et al.
Publicado: (2015)

Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts
por: Kang, Wenjing, et al.
Publicado: (2017)

Influence of Disease Duration on Circulating Levels of miRNAs in Children and Adolescents with New Onset Type 1 Diabetes
por: Samandari, Nasim, et al.
Publicado: (2018)

Associating transcription factors and conserved RNA structures with gene regulation in the human brain
por: Hecker, Nikolai, et al.
Publicado: (2017)

Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression
por: Bergholdt, Regine, et al.
Publicado: (2012)

A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells
por: Vestergaard, Anna Lindeløv, et al.
Publicado: (2016)

Transcripts with in silico predicted RNA structure are enriched everywhere in the mouse brain
por: Seemann, Stefan E, et al.
Publicado: (2012)

Circulating Levels of MicroRNA from Children with Newly Diagnosed Type 1 Diabetes and Healthy Controls: Evidence That miR-25 Associates to Residual Beta-Cell Function and Glycaemic Control during Disease Progression
por: Nielsen, Lotte B., et al.
Publicado: (2012)

Erratum to “Circulating Levels of MicroRNA from Children with Newly Diagnosed Type 1 Diabetes and Healthy Controls: Evidence That miR-25 Associates to Residual Beta-Cell Function and Glycaemic Control during Disease Progression”
por: Nielsen, Lotte B., et al.
Publicado: (2012)

Pro-Inflammatory Cytokines Promote the Transcription of Circular RNAs in Human Pancreatic β Cells
por: Kaur, Simranjeet, et al.
Publicado: (2022)

Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?
por: Egefjord, Lærke, et al.
Publicado: (2009)

Identification and characterization of novel conserved RNA structures in Drosophila
por: Kirsch, Rebecca, et al.
Publicado: (2018)

Breast Milk-Derived Extracellular Vesicles Enriched in Exosomes From Mothers With Type 1 Diabetes Contain Aberrant Levels of microRNAs
por: Mirza, Aashiq H., et al.
Publicado: (2019)

Differentially Expressed miRNAs in Ulcerative Colitis and Crohn’s Disease
por: Yarani, Reza, et al.
Publicado: (2022)

A Regression-based K nearest neighbor algorithm for gene function prediction from heterogeneous data
por: Yao, Zizhen, et al.
Publicado: (2006)

Comparative Structure Analysis of the Multi-Domain, Cell Envelope Proteases of Lactic Acid Bacteria
por: Christensen, Lise Friis, et al.
Publicado: (2023)

Plasma Exosome-Enriched Extracellular Vesicles From Lactating Mothers With Type 1 Diabetes Contain Aberrant Levels of miRNAs During the Postpartum Period
por: Frørup, Caroline, et al.
Publicado: (2021)

β Cell and Autophagy: What Do We Know?
por: Mohammadi-Motlagh, Hamid-Reza, et al.
Publicado: (2023)

Type 1 diabetes genome-wide association studies: not to be lost in translation
por: Pociot, Flemming
Publicado: (2017)

The vertebrate genome annotation (Vega) database
por: Wilming, L. G., et al.
Publicado: (2008)

The Vertebrate Genome Annotation (Vega) database
por: Ashurst, J. L., et al.
Publicado: (2005)

Emerging applications of read profiles towards the functional annotation of the genome
por: Pundhir, Sachin, et al.
Publicado: (2015)

High Glucose Suppresses Human Islet Insulin Biosynthesis by Inducing miR-133a Leading to Decreased Polypyrimidine Tract Binding Protein-Expression
por: Fred, Rikard G., et al.
Publicado: (2010)

Translation affects YoeB and MazF messenger RNA interferase activities by different mechanisms
por: Christensen-Dalsgaard, Mikkel, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_kavcf3isu2o9hbe9dsjge79o4k