Heritable L1 retrotransposition in the mouse primordial germline and early embryo

LINE-1 (L1) retrotransposons are a noted source of genetic diversity and disease in mammals. To expand its genomic footprint, L1 must mobilize in cells that will contribute their genetic material to subsequent generations. Heritable L1 insertions may therefore arise in germ cells and in pluripotent...

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Detalles Bibliográficos
Autores principales: Richardson, Sandra R., Gerdes, Patricia, Gerhardt, Daniel J., Sanchez-Luque, Francisco J., Bodea, Gabriela-Oana, Muñoz-Lopez, Martin, Jesuadian, J. Samuel, Kempen, Marie-Jeanne H.C., Carreira, Patricia E., Jeddeloh, Jeffrey A., Garcia-Perez, Jose L., Kazazian, Haig H., Ewing, Adam D., Faulkner, Geoffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538555/
https://www.ncbi.nlm.nih.gov/pubmed/28483779
http://dx.doi.org/10.1101/gr.219022.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538555/
https://www.ncbi.nlm.nih.gov/pubmed/28483779
http://dx.doi.org/10.1101/gr.219022.116

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