DNA replication timing during development anticipates transcriptional programs and parallels enhancer activation

In dividing cells, DNA replication occurs in a precise order, but many questions remain regarding the mechanisms of replication timing establishment and regulation. We now have generated genome-wide, high-resolution replication timing maps throughout zebrafish development. Unexpectedly, in the rapid...

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Detalles Bibliográficos
Autores principales: Siefert, Joseph C., Georgescu, Constantin, Wren, Jonathan D., Koren, Amnon, Sansam, Christopher L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538556/
https://www.ncbi.nlm.nih.gov/pubmed/28512193
http://dx.doi.org/10.1101/gr.218602.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538556/
https://www.ncbi.nlm.nih.gov/pubmed/28512193
http://dx.doi.org/10.1101/gr.218602.116

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