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DNA replication timing during development anticipates transcriptional programs and parallels enhancer activation
In dividing cells, DNA replication occurs in a precise order, but many questions remain regarding the mechanisms of replication timing establishment and regulation. We now have generated genome-wide, high-resolution replication timing maps throughout zebrafish development. Unexpectedly, in the rapid...
Autores principales: | Siefert, Joseph C., Georgescu, Constantin, Wren, Jonathan D., Koren, Amnon, Sansam, Christopher L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538556/ https://www.ncbi.nlm.nih.gov/pubmed/28512193 http://dx.doi.org/10.1101/gr.218602.116 |
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