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Structural and functional analysis of the GABARAP interaction motif (GIM)

Through the canonical LC3 interaction motif (LIR), [W/F/Y]‐X(1)‐X(2)‐[I/L/V], protein complexes are recruited to autophagosomes to perform their functions as either autophagy adaptors or receptors. How these adaptors/receptors selectively interact with either LC3 or GABARAP families remains unclear....

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Detalles Bibliográficos
Autores principales: Rogov, Vladimir V, Stolz, Alexandra, Ravichandran, Arvind C, Rios‐Szwed, Diana O, Suzuki, Hironori, Kniss, Andreas, Löhr, Frank, Wakatsuki, Soichi, Dötsch, Volker, Dikic, Ivan, Dobson, Renwick CJ, McEwan, David G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538626/
https://www.ncbi.nlm.nih.gov/pubmed/28655748
http://dx.doi.org/10.15252/embr.201643587