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A synthetic urinary probe–coated nanoparticles sensitive to fibroblast activation protein α for solid tumor diagnosis

We developed fibroblast activation protein α (FAPα)-sensitive magnetic iron oxide nanoparticles (MNPs) by conjugating a substrate-reporter tandem peptide as a synthetic biomarker to the surface of MNPs (marker-MNPs). In vitro, the marker-MNPs showed stability when treated with serum or urine and exh...

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Detalles Bibliográficos
Autores principales: Feng, Xinwei, Wang, Qifan, Liao, Yuehua, Zhou, Xie, Wang, Yidan, Liu, Wanli, Zhang, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538687/
https://www.ncbi.nlm.nih.gov/pubmed/28794628
http://dx.doi.org/10.2147/IJN.S139039