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Overexpression of mitochondrial serine hydroxyl-methyltransferase 2 is associated with poor prognosis and promotes cell proliferation and invasion in gliomas

Mitochondrial serine hydroxyl-methyltransferase 2 (SHMT2), participating in the synthesis of mitochondrial thymidine monophosphate, has been reported to drive glioma cell survival in ischemia. However, its clinical relevance in gliomas remains unclear. In the current study, immunohistochemistry was...

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Detalles Bibliográficos
Autores principales: Wu, Ming, Wanggou, Siyi, Li, Xuejun, Liu, Qing, Xie, Yuanyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538688/
https://www.ncbi.nlm.nih.gov/pubmed/28794642
http://dx.doi.org/10.2147/OTT.S130409