Repeated administration of mazindol reduces spontaneous pain-related behaviors without modifying bone density and microarchitecture in a mouse model of complete Freund’s adjuvant-induced knee arthritis

BACKGROUND: The role of dopaminergic system in the development of rheumatoid arthritis-related pain, a major symptom in this disease, has not been explored. Therefore, the anti-nociceptive effect of mazindol, a dopamine uptake inhibitor, was evaluated in a model of complete Freund’s adjuvant (CFA)-i...

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Detalles Bibliográficos
Autores principales: Robledo-González, LE, Martínez-Martínez, A, Vargas-Muñoz, VM, Acosta-González, RI, Plancarte-Sánchez, R, Anaya-Reyes, M, Fernández del Valle-Laisequilla, C, Reyes-García, JG, Jiménez-Andrade, JM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538698/
https://www.ncbi.nlm.nih.gov/pubmed/28794657
http://dx.doi.org/10.2147/JPR.S136581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538698/
https://www.ncbi.nlm.nih.gov/pubmed/28794657
http://dx.doi.org/10.2147/JPR.S136581

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