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Crystal structure of mimivirus uracil-DNA glycosylase

Cytosine deamination induced by stresses or enzymatic catalysis converts deoxycytidine into deoxyuridine, thereby introducing a G to A mutation after DNA replication. Base-excision repair to correct uracil to cytosine is initiated by uracil-DNA glycosylase (UDG), which recognizes and eliminates urac...

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Detalles Bibliográficos
Autores principales: Kwon, Eunju, Pathak, Deepak, Chang, Hyeun Wook, Kim, Dong Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538708/
https://www.ncbi.nlm.nih.gov/pubmed/28763516
http://dx.doi.org/10.1371/journal.pone.0182382