Impact of nucleic acid and methylated H3K9 binding activities of Suv39h1 on its heterochromatin assembly

SUV39H is the major histone H3 lysine 9 (H3K9)-specific methyltransferase that targets pericentric regions and is crucial for assembling silent heterochromatin. SUV39H recognizes trimethylated H3K9 (H3K9me3) via its chromodomain (CD), and enriched H3K9me3 allows SUV39H to target specific chromosomal...

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Detalles Bibliográficos
Autores principales: Shirai, Atsuko, Kawaguchi, Takayuki, Shimojo, Hideaki, Muramatsu, Daisuke, Ishida-Yonetani, Mayumi, Nishimura, Yoshifumi, Kimura, Hiroshi, Nakayama, Jun-ichi, Shinkai, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538823/
https://www.ncbi.nlm.nih.gov/pubmed/28760201
http://dx.doi.org/10.7554/eLife.25317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538823/
https://www.ncbi.nlm.nih.gov/pubmed/28760201
http://dx.doi.org/10.7554/eLife.25317

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