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Multiple-response regression analysis links magnetic resonance imaging features to de-regulated protein expression and pathway activity in lower grade glioma

BACKGROUND AND PURPOSE: Lower grade gliomas (LGGs), lesions of WHO grades II and III, comprise 10-15% of primary brain tumors. In this first-of-a-kind study, we aim to carry out a radioproteomic characterization of LGGs using proteomics data from the TCGA and imaging data from the TCIA cohorts, to o...

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Detalles Bibliográficos
Autores principales: Lehrer, Michael, Bhadra, Anindya, Ravikumar, Visweswaran, Chen, James Y., Wintermark, Max, Hwang, Scott N., Holder, Chad A., Huang, Erich P., Fevrier-Sullivan, Brenda, Freymann, John B., Rao, Arvind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538849/
https://www.ncbi.nlm.nih.gov/pubmed/28781988
http://dx.doi.org/10.18632/oncoscience.353