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Down-Regulation of Tim-3 in Monocytes and Macrophages in Plasmodium Infection and Its Association with Parasite Clearance

T-cell immunoglobulin and mucin-domain-containing molecule 3 (Tim-3) has complicated roles in regulating monocytes and macrophages in various diseases and it tends to be an inhibitory molecule to facilitate the immune escape of parasites in malaria. However, the mechanisms of Tim-3 mediated response...

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Detalles Bibliográficos
Autores principales: Hou, Nan, Jiang, Ning, Zou, Yang, Piao, Xianyu, Liu, Shuai, Li, Shanshan, Chen, Qijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539084/
https://www.ncbi.nlm.nih.gov/pubmed/28824565
http://dx.doi.org/10.3389/fmicb.2017.01431