DNA Methylation of Synaptic Genes in the Prefrontal Cortex Is Associated with Aging and Age-Related Cognitive Impairment

The current study investigates DNA methylation as a possible epigenetic regulator of transcription associated with aging and cognitive function. Young and aged male Fischer 344 rats were behaviorally characterized on a set shifting task, and whole genome bisulfite sequencing was employed to profile...

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Detalles Bibliográficos
Autores principales: Ianov, Lara, Riva, Alberto, Kumar, Ashok, Foster, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539085/
https://www.ncbi.nlm.nih.gov/pubmed/28824413
http://dx.doi.org/10.3389/fnagi.2017.00249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539085/
https://www.ncbi.nlm.nih.gov/pubmed/28824413
http://dx.doi.org/10.3389/fnagi.2017.00249

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