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Human Retrotransposon Insertion Polymorphisms Are Associated with Health and Disease via Gene Regulatory Phenotypes

The human genome hosts several active families of transposable elements (TEs), including the Alu, LINE-1, and SVA retrotransposons that are mobilized via reverse transcription of RNA intermediates. We evaluated how insertion polymorphisms generated by human retrotransposon activity may be related to...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Norris, Emily T., Jordan, I. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539088/
https://www.ncbi.nlm.nih.gov/pubmed/28824558
http://dx.doi.org/10.3389/fmicb.2017.01418