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Structure of the C-terminal domain of TRADD reveals a novel fold in the death domain superfamily

The TNFR1-associated death domain protein (TRADD) is an intracellular adaptor protein involved in various signaling pathways, such as antiapoptosis. Its C-terminal death domain (DD) is responsible for binding other DD-containing proteins including the p75 neurotrophin receptor (p75(NTR)). Here we pr...

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Detalles Bibliográficos
Autores principales: Zhang, Ning, Yuan, Wensu, Fan, Jing-Song, Lin, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539145/
https://www.ncbi.nlm.nih.gov/pubmed/28765645
http://dx.doi.org/10.1038/s41598-017-07348-9