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Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcription

Bmal1 (encoded by Arntl gene) is a core circadian clock gene that regulates various genes involved in circadian rhythm. Although Bmal1 is expressed rhythmically in macrophages, the role of Bmal1 in the regulation of their cellular function remains insufficiently understood. Here, we report that Bmal...

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Detalles Bibliográficos
Autores principales: Oishi, Yumiko, Hayashi, Shinichiro, Isagawa, Takayuki, Oshima, Motohiko, Iwama, Atsushi, Shimba, Shigeki, Okamura, Hitoshi, Manabe, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539165/
https://www.ncbi.nlm.nih.gov/pubmed/28765524
http://dx.doi.org/10.1038/s41598-017-07100-3