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Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcription
Bmal1 (encoded by Arntl gene) is a core circadian clock gene that regulates various genes involved in circadian rhythm. Although Bmal1 is expressed rhythmically in macrophages, the role of Bmal1 in the regulation of their cellular function remains insufficiently understood. Here, we report that Bmal...
Autores principales: | Oishi, Yumiko, Hayashi, Shinichiro, Isagawa, Takayuki, Oshima, Motohiko, Iwama, Atsushi, Shimba, Shigeki, Okamura, Hitoshi, Manabe, Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539165/ https://www.ncbi.nlm.nih.gov/pubmed/28765524 http://dx.doi.org/10.1038/s41598-017-07100-3 |
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