Intrinsic Plasma Cell Differentiation Defects in B Cell Expansion with NF-κB and T Cell Anergy Patient B Cells

B cell Expansion with NF-κB and T cell Anergy (BENTA) disease is a novel B cell lymphoproliferative disorder caused by germline, gain-of-function mutations in the lymphocyte scaffolding protein CARD11, which drives constitutive NF-κB signaling. Despite dramatic polyclonal expansion of naive and imma...

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Detalles Bibliográficos
Autores principales: Arjunaraja, Swadhinya, Nosé, Brent D., Sukumar, Gauthaman, Lott, Nathaniel M., Dalgard, Clifton L., Snow, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539167/
https://www.ncbi.nlm.nih.gov/pubmed/28824638
http://dx.doi.org/10.3389/fimmu.2017.00913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539167/
https://www.ncbi.nlm.nih.gov/pubmed/28824638
http://dx.doi.org/10.3389/fimmu.2017.00913

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