CD14 is critical for TLR2-mediated M1 macrophage activation triggered by N-glycan recognition

Agonist interaction with Toll-like receptors (TLRs) induces T cell-mediated immunity, which is effective against intracellular pathogens. Consequently, TLR agonists are being tried as immunomodulatory agents. The lectin ArtinM targets TLR2 N-glycans on macrophages, induces cytokines production, and...

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Detalles Bibliográficos
Autores principales: da Silva, Thiago Aparecido, Zorzetto-Fernandes, André L. V., Cecílio, Nerry T., Sardinha-Silva, Aline, Fernandes, Fabrício Freitas, Roque-Barreira, Maria Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539197/
https://www.ncbi.nlm.nih.gov/pubmed/28765651
http://dx.doi.org/10.1038/s41598-017-07397-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539197/
https://www.ncbi.nlm.nih.gov/pubmed/28765651
http://dx.doi.org/10.1038/s41598-017-07397-0

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