Cargando…

Kininase 1 As a Preclinical Therapeutic Target for Kinin B(1) Receptor in Insulin Resistance

Kinin B1 receptor (B1R) contributes to insulin resistance, an early event in type 2 diabetes, through the upregulation and activation of the inducible form of nitric oxide synthase (iNOS), pro-inflammatory cytokines and the oxidative stress. This study addresses the hypothesis that inhibition of kin...

Descripción completa

Detalles Bibliográficos
Autores principales: Haddad, Youssef, Couture, Réjean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539221/
https://www.ncbi.nlm.nih.gov/pubmed/28824433
http://dx.doi.org/10.3389/fphar.2017.00509