Tropism, intracerebral distribution, and transduction efficiency of HIV- and SIV-based lentiviral vectors after injection into the mouse brain: a qualitative and quantitative in vivo study

Lentiviruses are suitable to transfer potential therapeutic genes into non-replicating cells such as neurons, but systematic in vivo studies on transduction of neural cells within the complete brain are missing. We analysed the distribution of transduced cells with respect to brain structure, virus...

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Detalles Bibliográficos
Autores principales: Hlavatý, Juraj, Tonar, Zbyněk, Renner, Matthias, Panitz, Sylvia, Petznek, Helga, Schweizer, Matthias, Schüle, Silke, Kloke, Björn-Philipp, Moldzio, Rudolf, Witter, Kirsti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539277/
https://www.ncbi.nlm.nih.gov/pubmed/28397143
http://dx.doi.org/10.1007/s00418-017-1569-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539277/
https://www.ncbi.nlm.nih.gov/pubmed/28397143
http://dx.doi.org/10.1007/s00418-017-1569-1

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