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The respiratory chain inhibitor rotenone affects peroxisomal dynamics via its microtubule-destabilising activity

Peroxisomes and mitochondria in mammalian cells are closely linked subcellular organelles, which maintain a redox-sensitive relationship. Their interplay and role in ROS signalling are supposed to impact on age-related and degenerative disorders. Whereas the generation of peroxisome-derived oxidativ...

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Detalles Bibliográficos
Autores principales: Passmore, Josiah B., Pinho, Sonia, Gomez-Lazaro, Maria, Schrader, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539279/
https://www.ncbi.nlm.nih.gov/pubmed/28523458
http://dx.doi.org/10.1007/s00418-017-1577-1