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The respiratory chain inhibitor rotenone affects peroxisomal dynamics via its microtubule-destabilising activity
Peroxisomes and mitochondria in mammalian cells are closely linked subcellular organelles, which maintain a redox-sensitive relationship. Their interplay and role in ROS signalling are supposed to impact on age-related and degenerative disorders. Whereas the generation of peroxisome-derived oxidativ...
Autores principales: | Passmore, Josiah B., Pinho, Sonia, Gomez-Lazaro, Maria, Schrader, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539279/ https://www.ncbi.nlm.nih.gov/pubmed/28523458 http://dx.doi.org/10.1007/s00418-017-1577-1 |
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