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A polymorphism in ABCC4 is related to efficacy of 5-FU/capecitabine-based chemotherapy in colorectal cancer patients

To investigate the association of microRNA (miRNA) binding-site polymorphisms in the drug transporter genes with the efficacy of 5-Fluorouracil (5-FU)/capecitabine-based chemotherapy in colorectal cancer (CRC), 6 polymorphisms were determined in 432 CRC patients by using DNA sequencing method. The i...

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Detalles Bibliográficos
Autores principales: Chen, Qi, Meng, Fanyi, Wang, Lei, Mao, Yong, Zhou, Huan, Hua, Dong, Zhang, Hongjian, Wang, Weipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539293/
https://www.ncbi.nlm.nih.gov/pubmed/28765596
http://dx.doi.org/10.1038/s41598-017-07491-3