Telomerase reverse transcriptase promotes chemoresistance by suppressing cisplatin-dependent apoptosis in osteosarcoma cells

Cisplatin is one of the most efficacious antimitotic drugs used in the treatment of a range of malignant tumors. However, treatment failures are common due to the development of chemoresistance. In addition to its telomere maintenance function, telomerase plays a pro-survival role, inducing decrease...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhengpei, Yu, Ling, Dai, Guo, Xia, Kezhou, Liu, Gaiwei, Song, Qi, Tao, Chunjie, Gao, Tian, Guo, Weichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539325/
https://www.ncbi.nlm.nih.gov/pubmed/28765565
http://dx.doi.org/10.1038/s41598-017-07204-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539325/
https://www.ncbi.nlm.nih.gov/pubmed/28765565
http://dx.doi.org/10.1038/s41598-017-07204-w

Ejemplares similares