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Cardiac spheroids as promising in vitro models to study the human heart microenvironment

Three-dimensional in vitro cell systems are a promising alternative to animals to study cardiac biology and disease. We have generated three-dimensional in vitro models of the human heart (“cardiac spheroids”, CSs) by co-culturing human primary or iPSC-derived cardiomyocytes, endothelial cells and f...

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Detalles Bibliográficos
Autores principales: Polonchuk, Liudmila, Chabria, Mamta, Badi, Laura, Hoflack, Jean-Christophe, Figtree, Gemma, Davies, Michael J., Gentile, Carmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539326/
https://www.ncbi.nlm.nih.gov/pubmed/28765558
http://dx.doi.org/10.1038/s41598-017-06385-8